Scopulariopsis brumptii

Colonies on potato dextrose agar at 25°C are initially white, become gray to grayish-black at maturity, have a moderate growth rate, and are somewhat floccose.

Hyphae are septate and hyaline. Conidiophores may occur singly or in penicillate groups. Annellides are approximately 5-10 x 2.5-3.5 µm, flash-shaped, and display cylindrical annellated zones varying from 0.8 — 1.5µm wide. Conidia are brown, occur in chains, have a truncate base, measure 4.0-5.5 x 3.5-4.5 µm, are subglobose, and mostly rough-walled [531] [2202], [1584].

Scopulariopsis brumptii has been reported as an agent of hypersensitivity pneumonitis in an addict [903].

AMB	CAS	ITRA	VORI
8 µg/ml=1	8 µg/ml=1	0.03 µg/ml=1	1 µg/ml=1
>16 µg/ml=1		>8 µg/ml=1	2 µg/ml=1

Drug/N	AMB/2	CAS/1	ITRA/2	VORI/2
MIC Range	8->16	8	0.03-8	1-2

* Fungus Testing Laboratory unpublished data (NCCLS M38-A)

PubMed

GenBank

Chains of conidia

References

531. de Hoog, G. S., J. Guarro, J. Gene, and M. J. Figueras. 2000. Atlas of Clinical Fungi, 2nd ed, vol. 1. Centraalbureau voor Schimmelcultures, Utrecht, The Netherlands.

903. Grieble, H. G., J. W. Rippon, N. Maliwan, and V. Daun. 1975. Scopulariopsosis and hypersensitivity pneumonitis in an addict. Ann. Intern. Med. 83:326-9.

1584. Morton, F. J., and G. Smith. 1963. The genera Scopulariopsis Bainer, Microascus Zukal, and Doratomyces Corda. Mycol. Pap. 86:1-96.

2202. Sutton, D. A., A. W. Fothergill, and M. G. Rinaldi (ed.). 1998. Guide to Clinically Significant Fungi, 1st ed. Williams & Wilkins, Baltimore.