Rhodotorula minuta Species

Colonies on Sabouraud dextrose agar at 25°C are pink, smooth and glossy but not mucoid.

On cornmeal following 72 hours incubation at 25°C, only globose yeast cells are produced (2.3-6.5 µm in diameter) [1270].

This isolate is urease positive, nitrate negative, fails to grow on media containing cycloheximide, and demonstrates variable growth at 30°C. Reports of disease in the literature include hip joint sepsis [501], endophthalmitis [1801], and catheter related sepsis in an HIV positive patient [857]. FTL isolates include recovery from blood and lymph node.

AMB	KETO	FLU	ITRA	VORI	POSA
0.25 µg/ml=2	0.5 µg/ml=2	32 µg/ml=1	0.25 µg/ml=2	0.25 µg/ml=1	0.06 µg/ml=1
		>64 µg/ml=2	1.0 µg/ml=1	4.0 µg/ml=1
			2.0 µg/ml=1	>8.0 µg/ml=1

Drug/N	AMB/2	FLU/3	ITRA/4	VORI/3	POSA/1	KETO/2
MIC Range	0.25	32->64	0.25-2.0	0.25->8.0	0.06	0.5

* Fungus Testing Laboratory unpublished data (CLSI M27-A2)

PubMed

GenBank

References

501. Cutrona, A. F., M. Shah, M. S. Himes, and M. A. Miladore. 2002. Rhodotorula minuta: an unusual fungal infection in hip-joint prosthesis. Am J Orthop. 31:137-40.

857. Goldani, L. Z., D. E. Craven, and A. M. Sugar. 1995. Central venous catheter infection with Rhodotorula minuta in a patient with AIDS taking suppressive doses of fluconazole. J Med Vet Mycol. 33:267-70.

1270. Kurtzman, C. P., and J. W. Fell (ed.). 2000. The Yeasts. A Taxonomic Study. Elsevier Scientific B.V., Amsterdam, The Netherlands.

1801. Pinna, A., F. Carta, S. Zanetti, S. Sanna, and L. A. Sechi. 2001. Endogenous Rhodotorula minuta and Candida albicans endophthalmitis in an injecting drug user. Br J Ophthalmol. 85:759.