Help! Please Register

  The Fungi

  Image Bank
  Lecture Bank
  Video Bank






  MIC Database

  Education &

  Good Books
  Events Calendar

  About Us

  Our Mission
  Editorial Board
  Editorial Staff
  Legal Stuff
  Privacy Policy

  The Fungi

  Image Bank
  Lecture Bank
  Video Bank

This page updated:
1/27/2007 9:23:00 AM

DoctorFungus - All Rights Reserved © 2007 Copyright
& Privacy Policy

Site built and designed for doctorfungus by Webillustrated

You are here: The Fungi > Descriptions >

Aspergillus versicolor
(Vuillemin) Tiraboschi, 1926

Macroscopic morphology

Colonies on potato dextrose agar at 25°C are variously colored (versicolored) and may range from very pale green, to greenish-beige, pinkish-green, salmon green, or dark green. Reverse is reddish to uncolored. Exudate, when present, is pink to reddish-brown. The growth rate is slow to moderate.

Microscopic morphology

Hyphae are septate and hyaline. Conidial heads are biseriate and loosely radiate. Conidiophores measure 120-700 µm in length, are hyaline to pale brown, smooth-walled and brittle (can see where many have "snapped off"). Vesicles are small (approximately 9-16 µm in diameter) and variably shaped, with metulae and phialides covering most of the vesicle. Reduced conidial structures resembling those seen in Penicillium species are common. Conidia measure 2.5-3 µm in diameter, are globose, and may be fine to distinctly roughened. Globose Hülle cells may also be present. Restricted growth at 35°C [531, 1215, 1875, 2202].

Special notes

Aspergillus versicolor has been reported as an agent of cutaneous disease, [800], onychomycosis[2247], otomycosis [521, 1972], osteomyelitis[1359], pulmonary disease[1051], and a mycetoma-like granuloma in a horse[1177]. Its mycotoxin, sterigmatocystin, has been studied in foodstuffs[1738, 1892] and in damp indoor environments[669].

FTL* in vitro susceptibility data

0.5 µg/ml=1 0.03 µg/ml=1 0.125 µg/ml=1 0.25 µg/ml=2 0.03 µg/ml=1 16 µg/ml=1
1.0 µg/ml=1 0.06 µg/ml=2 0.25 µg/ml=1 0.5 µg/ml=3   >64 µg/ml=9
2.0 µg/ml=5 0.25 µg/ml=1 0.5 µg/ml=3 1.0 µg/ml=2    
4.0 µg/ml=1 4.0 µg/ml=1 1.0 µg/ml=2 2.0 µg/ml=2    
8.0 µg/ml=1 32 µg/ml=1 4.0 µg/ml=1      
  >64 µg/ml=1        

Drug/N AMB/9 CAS/7 ITRA/8 VORI/9
MIC Range 0.5-8.0 0.03>64 0.125-1.0 0.25-2.0
MIC50 2.0 0.25 0.5 0.5
* Fungus Testing Laboratory unpublished data (NCCLS M38-A)





Biseriate fruiting heads
Biseriate fruiting heads


521. De Amicis, E. 1950. Clinical, mycological and pathogenic observations on three cases of otomycosis with Aspergillus versicolor. Boll Mal Orecch Gola Naso. 68:278-325.

531. de Hoog, G. S., J. Guarro, J. Gene, and M. J. Figueras. 2000. Atlas of Clinical Fungi, 2nd ed, vol. 1. Centraalbureau voor Schimmelcultures, Utrecht, The Netherlands.

669. Engelhart, S., A. Loock, D. Skutlarek, H. Sagunski, A. Lommel, H. Farber, and M. Exner. 2002. Occurrence of toxigenic Aspergillus versicolor isolates and sterigmatocystin in carpet dust from damp indoor environments. Appl Environ Microbiol. 68:3886-90.

800. Galimberti, R., A. Kowalczuk, I. H. Parra, M. G. Ramos, and V. Flores. 1998. Cutaneous aspergillosis: a report of six cases. Brit J Dermatol. 139:522-526.

1051. Hodgson, M. J., P. Morey, W. Y. Leung, L. Morrow, D. Miller, B. B. Jarvis, H. Robbins, J. F. Halsey, and E. Storey. 1998. Building-associated pulmonary disease from exposure to Stachybotrys chartarum and Aspergillus versicolor. J Occup Environ Med. 40:241-9.

1177. Keegan, K. G., C. L. Dillavou, S. E. Turnquist, and W. H. Fales. 1995. Subcutaneous mycetoma-like granuloma in a horse caused by Aspergillus versicolor. J Vet Diagn Invest. 7:564-7.

1215. Klich, M. A., and J. I. Pitt. 1988. A Laboratory Guide to Common Aspergillus Species and their Teleomorphs. Commonwealth Scientific and Industrial Research Organization, North Ryde, New South Wales, Australia.

1359. Liu, Z., T. Hou, Q. Shen, W. Liao, and H. Xu. 1995. Osteomyelitis of sacral spine caused by Aspergillus versicolor with neurologic deficits. Chin Med J (Engl). 108:472-5.

1738. Paul, P., and V. Thurm. 1979. Hygienic significance of sterigmatocystin in vegetable foods. 2. Production of sterigmatocystin by Aspergillus versicolor. Nahrung. 23:117-20.

1875. Raper, K. B., and D. I. Fennell. 1965. The genus Aspergillus. Williams & Wilkins, Baltimore.

1892. Reiss, J. 1976. Mycotoxins in foodstuffs. VI. Formation of sterigmatocystin in bread by Aspergillus versicolor. Z Lebensm Unters Forsch. 160:313-9.

1972. Rotoli, M., G. Sascaro, and S. Cavalieri. 2001. Aspergillus versicolor infection of the external auditory canal successfully treated with terbinafine. Dermatology. 202:143.

2202. Sutton, D. A., A. W. Fothergill, and M. G. Rinaldi (ed.). 1998. Guide to Clinically Significant Fungi, 1st ed. Williams & Wilkins, Baltimore.

2247. Torres-Rodriguez, J. M., N. Madrenys-Brunet, M. Siddat, O. Lopez-Jodra, and T. Jimenez. 1998. Aspergillus versicolor as cause of onychomycosis: report of 12 cases and susceptibility testing to antifungal drugs. J Eur Acad Dermatol Venereol. 11:25-31.

  Home | Image Bank | Lecture Bank | Knowledgebase | Site Map | Contact Us |
The Fungi | Mycoses | Drugs |
Laboratory | Education & Tools | About Us