Dr. Fungus: Fungi, Fungus, Fungal

Welcome to Doctor Fungus, your on-line reference to all things mycological!!

Title: Bringing in the New: How Can We Improve Clinical Trial Design Strategies for Invasive Fungal Infections?

An official event of the Mycoses Study Group Educational Committee

Educational Partner: PharmAdura, LLC

CME Accreditor: Postgraduate Institute for Medicine

Sponsored by: Merck & Co., Inc. and Enzon Pharmaceuticals

Proposed Faculty:

Peter G. Pappas, MD [moderator]
Professor of Medicine in the Medicine/Infectious Diseases Department
University of Alabama at Birmingham
Birmingham, Alabama

Dimitrios Konotyiannis, MD
Associate Professor
Department of Infectious Diseases
Infection Control and Employee Health
Director of Mycology Research Program
The University of Texas M. D. Anderson Cancer Center
Adjunct Associate Professor
University of Houston College of Pharmacy
Houston, Texas

Kieren Marr, MD
Adjunct Professor, Medicine
Director, Transplant Infectious Disease Program
Director, ID Clinical Research Center
Division of Infectious Diseases
Oregon Health and Science University
Portland, Oregon

Jack Sobel, MD
Professor and Chief, Division of Infectious Diseases
Wayne State University School of Medicine
Harper Hospital
Detroit, Michigan

Learning Objectives:

Describe design issues encountered in recent Candida, Aspergillus, Cryptococcus and endemic fungi studies
Propose methodologies to address design issues such as appropriate use of surrogate markers and control of patient comorbidities
List issues related to patient selection for clinical trials in IFIs
Define methods for assessing attributable mortality for IFIs
Review the value of serial fungal cultures in clinical trials

Agenda

4:00 PM   Registration

4:25 PM   Introductions/Overview
                Peter G. Pappas, MD

4:30 PM   Clinical Trials for Invasive Candidiasis
                Jack Sobel, MD

4:55 PM   Panel Discussion/Q&A

5:10 PM   Clinical Trials for Aspergillosis
                Kieren Marr, MD

5:35 PM   Panel Discussion/Q&A

5:50 PM   Clinical Trials for Uncommon Moulds
                Dimitrios Kontoyiannis, MD, ScD, FACP, FIDSA

6:15 PM   Panel Discussion/Q&A

6:30 PM   Question and Answer session and additional panel discussion
                Moderated by Peter G. Pappas, MD

6:45 PM   Adjourn