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Tinea capitis and Tinea favosa




Synonyms

Ringworm of the scalp and hair

Definition

Tinea capitis is the fungal infection of the scalp due to dermatophytes. The hair of head, eyebrows, eyelashes may also be involved. The skin may be involved alone, as is seen with infection due to Trichophyton rubrum.

There are three forms of hair infection. In the form known as endothrix, the infection begins by penetration of the hair, and the organism then grows up the interior main axis of the hair where it fragments into arthroconidia. A typical causative agent is T. tonsurans. The exception to the rule about arthroconidia formation is Trichophyton schoenleinii. This organism causes an endothrix-style growth, but without the arthrocondia. Instead, channels are formed within the hair shaft. This is useful diagnostically, as air bubbles move along these channels when an infected hair is immersed in a liquid. This later form of infection, as well as the clinical presentation of scutula, carries the special label Tinea favosa, or favus [402, 657].

In the form of hair infection known as ectothrix, the infection begins as in endothrix, but it then extends back out through the hair cuticle (the outer wall of the hair) and forms a mass of arthroconidia both within and around the hair shaft. A typical causative agent is Microsporum canis [840].

Epidemiology

Tinea capitis is characteristically a fungal infection affecting children between 4 and 14 years of age [321]. Although a large list of fungal pathogens have been implicated, Trichophyton tonsurans is responsible for more than 90% of cases in North America and the United Kingdom. Urban cases are commonly acquired from classmates or family members. Overcrowding, poor hygiene and protein malnutrition favor the occurrence of this disease [1447]. Cases caused by Microsporum canis occur sporadically and are acquired from puppies and kittens [1045].

Clinical manifestations

The diagnosis of tinea capitis should be suspected in any child older than 3 months with a scaly scalp. Differential diagnosis includes seborrheic dermatitis, atopic dermatitis, psoriasis, alopecia areata, trichotillomania, bacterial folliculitis, abscesses and neoplasias.

The forms of Tinea Capitis are:
CATEGORIES CLINICAL APPEARANCE
NonInflammatory
Diffuse scaly
Grey patch
Erythematous papule(s) around the hair shaft appear initially. Subsequently, one or several patches of scaly alopecia are seen where the hairs are broken just above the level of the scalp. The hair looks lusterless and gray because it is covered with arthrospores.
Inflammatory
Diffuse pustular
Kerion
Scattered painful pruritic pustular folliculitis generally associated with regional lymphadenopathy and even fever. In about 2-3 percent, boggy nodules studded with broken hairs and purulent sticky material ("kerion") appear. Scarring alopecia develops subsequently.
"Black dot" As it is related to the endothrix variety of infection, hairs become notably fragile and break easily at the level of the scalp. The rest of the infected follicle looks like "black dots". Variable degrees of scaling and inflammation are seen.

From [1045] [1447]

Prognosis and therapy

In contrast with other forms of dermatophytoses, tinea capitis should be treated with oral agents. Griseofulvin and ketoconazole have been extensively used, however terbinafine, itraconazole, and fluconazole are also recomended [616].

DRUG REGIMEN NOTES
Griseofulvin 10 mg/kg/day x 8-10 weeks Ingest with fatty food to increase absorption
Itraconazole 5 mg/kg/day x 1-4 weeks Take oral solution without food
Terbinafine < 20 kg: 62.5 mg/day
20 — 40 kg: 125 mg/day x 4 wks
> 40 kg: 250 mg/day
 

From [1045]

A pruritic papular rash that commonly affects the outer helix of the ears may appear after the introduction of therapy and should not be confused with a drug reaction [1045].

Some patients may need either intralesional or short oral courses of corticosteroids. Surgical approaches such as incision and drainage of kerion are not suggested. Bacterial superinfections are common, and antibiotic treatments may be neccesary [616, 1045].

Topical therapy with selenium sulphide, and povidone iodine shampoos are recommended twice a week to reduce infectivity, but should not be used as the sole therapeutic agents [1045].

Mycology(principal dermatophytes)

Natural habitat

Animals, humans, soil



Synonyms

Favus

Definition

Tinea favosa is usually considered a variety of Tinea capitis because it classically involves the scalp, however, this mycotic infection may also involve glabrous skin and nails.

Epidemiology

Favus is a disease of rural areas where poor hygiene and malnutrition are frequent [1447]. It generally affects groups of family, reason why it is postulated that prolonged and intimate contact is neccesary for transmission [1137].

Clinical manifestations

Favus is characterized by the occurrence of dense masses of mycelium and epithelial debris forming yellowish cup-shaped crusts called scutula. The scutulum develops at the surface of a hair follicle with the shaft in the center of the raised lesion. Removal of these crusts reveals an oozing, moist, red base. After a period of years, atrophy of the skin occurs leaving a cicatricial alopecia and scarring. Scutula may form on the scalp or the glabrous skin.

Prognosis and therapy

Therapeutic considerations for tinea favus are the same as for Tinea capitis [616].

Mycology

Natural habitat

Humans, soil



Favus
Favus



References

321. Bronson, D. M., D. R. Desai, S. Barsky, and S. M. Foley. 1983. An epidemic of infection with Trichophyton tonsurans revealed in a 20- year survey of fungal infections in Chicago. J Am Acad Dermatol. 8:322-30.

402. Ceburkovas, O., R. A. Schwartz, and C. K. Janniger. 2000. Tinea capitis: current concepts. J Dermatol. 27:144-8.

616. Drake, L. A., S. M. Dinehart, E. R. Farmer, R. W. Goltz, G. F. Graham, M. K. Hordinsky, C. W. Lewis, D. M. Pariser, J. W. Skouge, S. B. Webster, D. C. Whitaker, B. Butler, B. J. Lowery, B. E. Elewski, M. L. Elgart, P. H. Jacobs, J. L. Lesher, Jr., and R. K. Scher. 1996. Guidelines of care for superficial mycotic infections of the skin: tinea capitis and tinea barbae. Guidelines/Outcomes Committee. American Academy of Dermatology. J Am Acad Dermatol. 34:290-4.

657. Elewski, B. E. 2000. Tinea capitis: a current perspective. J Am Acad Dermatol. 42:1-20; quiz 21-4.

840. Ginarte, M., M. Pereiro, Jr., V. Fernandez-Redondo, and J. Toribio. 2000. Case Reports. Pityriasis amiantacea as manifestation of tinea capitis due to Microsporum canis [letter]. Mycoses. 43:93-6.

1045. Higgins, E. M., L. C. Fuller, and C. H. Smith. 2000. Guidelines for the management of tinea capitis. Brit J Dermatol. 143:53-58.

1137. Joly, J., G. Delage, P. Auger, and P. Ricard. 1978. Favus: twenty indigenous cases in the province of Quebec. Arch Dermatol. 114:1647-8.

1447. Martin, A. G., and G. S. Kobayashi. 1993. Fungal diseases with cutaneous involvement, p. 2421-2451. In T. B. Fitzpatrick (ed.), Dermatology in general medicine, vol. 2. McGraw-Hill, New York.



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